SCHEMBL24473566

SCHEMBL24473566

C=CC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 9/20 0.48
▸ NPY1R P25929 7/20 0.48
▸ NPY2R P49146 5/20 0.48
▸ NTSR2 O95665 7/20 0.47
▸ NTSR1 P30989 2/20 0.47
▸ NPY5R Q15761 4/20 0.42
▸ FOLH1 Q04609 1/20 0.41
▸ GHSR Q92847 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24473314 1.00 NPY4R (0.48) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473521 1.00 NPY4R (0.48) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473470 0.90 NPY4R (0.56) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473382 0.90 NPY4R (0.56) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473300 0.90 NPY4R (0.56) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473479 0.90 NPY4R (0.56) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473513 0.90 NPY4R (0.56) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473464 0.90 NPY4R (0.56) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473421 0.90 NPY4R (0.56) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL24473383 0.90 NPY4R (0.56) NPY4RNPY1RNPY2RNTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168383-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2022-06-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168383-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN VIP, NTSR2, VIPR2 NPY4R 62/4885NPY1R 41/4885NPY2R 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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