Iodide

Iodide

SCHEMBL2447417

CCCCN1C=Cc2ccccc2C1.I

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 1/20 0.33
CHRM3 known ✓ P20309 1/20 0.33
HDAC3 O15379 1/20 0.56
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
SIGMAR1 Q99720 10/20 0.37
SETD7 Q8WTS6 1/20 0.37
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
MITF O75030 1/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
RECQL P46063 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
EBP Q15125 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1127857 0.98 HDAC3 (0.57) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL28570347 0.97 HDAC3 (0.56) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
Iodide SCHEMBL10749222 0.95 HDAC3 (0.58) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
Iodide SCHEMBL11872589 0.94 HDAC3 (0.60) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL9161505 0.94 HDAC3 (0.59) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL1961830 0.92 HDAC3 (0.61) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL9512254 0.92 HDAC3 (0.61) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL1963183 0.92 HDAC3 (0.61) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL1963055 0.92 HDAC3 (0.61) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL1959030 0.92 HDAC3 (0.61) HDAC3ALDH1A1CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61282363-A None JP disclosed
JP-1070471-A None JP disclosed
EP-1650328-B1 METHOD FOR FORMING OXIDE FILM ON METAL SURFACE USING IONIC LIQUID, ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF KANEKA CORP (JP) 2016-10-19 EP disclosed
EP-2540875-A1 Electrolytic capacitor including ionic liquid in electrolyte KANEKA CORPORATION (JP) 2013-01-02 EP disclosed
US-8034956-B2 Ionic liquid and method for producing the same, method for forming oxide film on metal surface, electrolyte capacitor and electrolyte KANEKA CORPORATION (JP) 2011-10-11 US disclosed
US-8014128-B2 Method for forming oxide film on metal surface using ionic liquid, electrolytic capacitor and electrolyte thereof KANEKA CORPORATION (JP) 2011-09-06 US disclosed
US-7746623-B2 Electrolytic capacitor and electrolyte thereof KANEKA CORPORATION (JP) 2010-06-29 US disclosed
US-20080304208-A1 ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF KANEKA CORPORATION 2008-12-11 US disclosed
US-20070263341-A1 Ionic Liquid and Method for Producing the Same, Method for Forming Oxide Film on Metal Surface, Electrolytic Capicitor and Electrolyte KANEKA CORPORATION (JP) 2007-11-15 US disclosed
US-20060181835-A1 Method for forming oxide film on metal surface using ionic liquid, electrolytic capacitor and electrolyte thereof KANEKA CORPORATION (JP) 2006-08-17 US disclosed
EP-1650328-A1 METHOD FOR FORMING OXIDE FILM ON METAL SURFACE USING IONIC LIQUID, ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF KANEKA CORPORATION (JP) 2006-04-26 EP disclosed
US-4889934-A Organic mixed complex NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-12-26 US disclosed
JP-S6470471-A PRODUCTION OF TCNQ COMPLEX MITSUBISHI GAS CHEMICAL CO 1989-03-15 JP disclosed
US-4801713-A ELECTROCONDUCTIVE COMPLEXES NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-01-31 US disclosed
JP-S61282363-A SUBSTITUTED TETRACYANOQUINODIMETHANE (TCNQ) COMPLEX WAKO PURE CHEM IND LTD 1986-12-12 JP disclosed
US-4568494-A Process for the preparation of TCNQ complexes BAYER AKTIENGESELLSCHAFT (DE) 1986-02-04 US disclosed