Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.67 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | IL1B | P01584 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.53 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.52 |
| ▸ | CCNK | O75909 | 1/20 | 0.51 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383207 | 0.92 | DDB1 (0.73) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL24474344 | 0.91 | DDB1 (0.69) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL24474217 | 0.90 | DDB1 (0.71) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL23884265 | 0.88 | DDB1 (0.66) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL23884160 | 0.86 | CRBN (0.62) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL2381932 | 0.85 | DDB1 (0.77) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL29794426 | 0.85 | DDB1 (0.77) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL2381262 | 0.85 | DDB1 (0.77) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL31027941 | 0.84 | DDB1 (0.73) | CRBNDDB1HDAC1HDAC2TNF | |
| SCHEMBL2381765 | 0.84 | DDB1 (0.79) | CRBNDDB1HDAC1HDAC2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111521-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州多域生物技术有限公司 | 2022-06-02 | — | — | WO | disclosed |