SCHEMBL244743

SCHEMBL244743

CCCCCCCCCCCCCCCCCCc1cccc(C(=O)O)c1C(=O)O.[NaH]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 7/20 0.70
MCL1 Q07820 7/20 0.70
BCL2L1 Q07817 6/20 0.70
BAK1 Q16611 6/20 0.70
KAT8 Q9H7Z6 3/20 0.70
PPARA Q07869 3/20 0.70
PPARG P37231 2/20 0.70
SAE1 Q9UBE0 2/20 0.70
EP300 Q09472 2/20 0.70
KAT5 Q92993 2/20 0.70
KAT2A Q92830 1/20 0.70
KAT2B Q92831 1/20 0.70
F7 P08709 3/20 0.60
F3 P13726 3/20 0.60
MMP2 P08253 2/20 0.60
KDM4E B2RXH2 1/20 0.60
MAPT P10636 1/20 0.60
ALOX15 P16050 1/20 0.60
ECE1 P42892 1/20 0.60
SGMS1 Q86VZ5 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28099346 1.00 BID (0.70) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL23277 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL485756 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL301487 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5519496 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5424052 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL3033684 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL10767415 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL3258790 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL300614 0.98 BID (0.72) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710329-B Personal care compositions 高露洁-棕榄公司 2024-04-05 CN disclosed
CN-113164361-B Personal care compositions 高露洁-棕榄公司 2024-04-02 CN disclosed
CN-117545510-A Rheology modifier comprising an inverse acrylamide polymer emulsion and architectural coating compositions derived therefrom 赫尔克里士有限公司 2024-02-09 CN disclosed
CN-113710329-A Personal care compositions 高露洁-棕榄公司 2021-11-26 CN disclosed
CN-113164361-A Personal care compositions 高露洁-棕榄公司 2021-07-23 CN disclosed
EP-1938810-B1 AMELIORATING AGENT FOR METABOLIC SYNDROME FUJI CHEM IND CO LTD (JP) 2014-06-18 EP disclosed
US-8252362-B2 Method of measuring coating quantity and method of predicting dissolution behavior EISAI R&D MANAGEMENT CO., LTD. (JP) 2012-08-28 US disclosed
US-20120004297-A1 Agent for alleviating vascular failure NAOKI HIGASHI 2012-01-05 US disclosed
US-20090269484-A1 Method of measuring coating quantity and method of predicting dissolution behavior EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-10-29 US disclosed
US-20090099255-A1 Agent for Alleviating Vascular Failure FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-04-16 US disclosed
EP-1938810-A1 AMELIORATING AGENT FOR METABOLIC SYNDROME FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2008-07-02 EP disclosed
EP-1864658-A1 AGENT FOR ALLEVIATING VASCULAR INSUFFICIENCY FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-12 EP disclosed
EP-1857809-A1 METHOD OF MEASURING COATING AMOUNT AND METHOD OF ESTIMATING ELUTION BEHAVIOR Eisai R&D Management Co., Ltd. (JP) 2007-11-21 EP disclosed
US-6562926-B1 Method for producing water-soluble homopolymers and copolymers, comprising oligoalkylene-imine side chains of the general formula (I), wherein (AI)m, m, Y and x have the definitions given in claim 1, by radical polymerization for BASF AKTIENGESELLSCHAFT (DE) 2003-05-13 US disclosed