Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13107150 | 0.86 | KMT2A (0.64) | KMT2ACYP2C19HTTCYP2D6SMN1; SMN2 | |
| SCHEMBL20878524 | 0.84 | POLB (0.54) | KMT2AEPHX1CYP2C19CYP2D6SMN1; SMN2 | |
| SCHEMBL2603264 | 0.81 | HCRTR2 (0.45) | KMT2ACYP2C19HTTHCRTR2LMNA | |
| SCHEMBL26228168 | 0.80 | KMT2A (0.43) | KMT2ACYP2C19HTTSMN1; SMN2POLB | |
| SCHEMBL7863949 | 0.80 | KMT2A (0.48) | KMT2AKDM4EEPHX1CYP2C19HTT | |
| SCHEMBL12233194 | 0.80 | KMT2A (0.48) | KMT2AKDM4EEPHX1CYP2C19HTT | |
| SCHEMBL2603261 | 0.79 | HTT (0.45) | KMT2ACYP2C19HTTHCRTR2LMNA | |
| SCHEMBL2603259 | 0.79 | KMT2A (0.42) | KMT2AKDM4ECYP2C19HTTHSD17B10 | |
| SCHEMBL2603260 | 0.78 | POLB (0.58) | KMT2ASMN1; SMN2POLBHCRTR2LMNA | |
| SCHEMBL7862569 | 0.78 | KMT2A (0.47) | KMT2AKDM4EEPHX1CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111521-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州多域生物技术有限公司 | 2022-06-02 | — | — | WO | disclosed |