Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 18/20 | 0.66 |
| ▸ | JAK2 | O60674 | 11/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24474970 | 1.00 | JAK1 (0.66) | JAK1JAK2 | |
| SCHEMBL29430979 | 1.00 | JAK1 (0.66) | JAK1JAK2 | |
| SCHEMBL29431031 | 0.94 | JAK1 (0.66) | JAK1JAK2 | |
| SCHEMBL24474633 | 0.94 | JAK1 (0.66) | JAK1JAK2 | |
| SCHEMBL26078074 | 0.94 | JAK1 (0.66) | JAK1JAK2 | |
| SCHEMBL24474962 | 0.87 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL29431074 | 0.87 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL24474783 | 0.87 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL29431139 | 0.87 | JAK1 (0.64) | JAK1JAK2 | |
| SCHEMBL24474628 | 0.87 | JAK1 (0.64) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253375-A1 | AMIDE COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Artivila (ShenZhen) Innovation Center, Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022111499-A1 | AMIDE COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 深圳铂立健医药有限公司 | 2022-06-02 | — | — | WO | disclosed |