⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649000 | 0.86 | — | — | |
| SCHEMBL1914090 | 0.84 | — | — | |
| SCHEMBL7219700 | 0.84 | — | — | |
| SCHEMBL1914093 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL29202608 | 0.82 | KAT2B (0.40) | — | |
| SCHEMBL25091520 | 0.77 | — | — | |
| SCHEMBL18155989 | 0.77 | — | — | |
| SCHEMBL24477208 | 0.77 | — | — | |
| SCHEMBL16083123 | 0.77 | — | — | |
| SCHEMBL15281313 | 0.77 | KAT2B (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220362396-A1 | AMINO-PYRAZINECARBOXAMIDE COMPOUNDS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2022-11-17 | — | — | US | disclosed |
| US-20220169660-A1 | CYCLIC AMINO-PYRAZINECARBOXAMIDE COMPOUNDS AND USES THEREOF | SILVERBACK THERAPEUTICS INC (US) | 2022-06-02 | — | — | US | disclosed |