SCHEMBL2447745

SCHEMBL2447745

CCCc1cc(N)ccc1Oc1ccc(C2(c3ccc(Oc4ccc(N)cc4CCC)c(C)c3)c3ccccc3-c3ccccc32)cc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 1/20 0.44
OPRK1 P41145 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
SLC6A4 P31645 5/20 0.33
SLC6A2 P23975 3/20 0.33
SLC6A3 Q01959 3/20 0.33
PDK2 Q15119 3/20 0.32
CHEK1 O14757 1/20 0.31
PRKD3 O94806 1/20 0.31
MAP4K4 O95819 1/20 0.31
RET P07949 1/20 0.31
MET P08581 1/20 0.31
PDGFRA P16234 1/20 0.31
FLT1 P17948 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2441622 0.95 KDM4E (0.44) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL29418399 0.95 KDM4E (0.44) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL3877820 0.93 ESR1 (0.43) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL2443397 0.93 ESR1 (0.43) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL2441683 0.93 KDM4E (0.49) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL2441643 0.91 ESR1 (0.47) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL2450323 0.90 KDM4E (0.43) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL2441121 0.89 MEN1 (0.46) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL2443557 0.89 MEN1 (0.46) ESR1ESR2KDM4EMEN1MAPT
SCHEMBL29418392 0.88 MAPT (0.54) ESR1ESR2KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
US-8022110-B2 Porous polyimide IBIDEN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100048745-A1 POROUS POLYIMIDE IBIDEN CO., LTD (JP) 2010-02-25 US disclosed
EP-2128193-A1 POROUS POLYIMIDE Ibiden Co., Ltd. (JP) 2009-12-02 EP disclosed