Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.54 |
| ▸ | CDK2 | P24941 | 20/20 | 0.54 |
| ▸ | CCND1 | P24385 | 15/20 | 0.54 |
| ▸ | CDK6 | Q00534 | 15/20 | 0.54 |
| ▸ | CDK1 | P06493 | 7/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.54 |
| ▸ | CDK4 | P11802 | 7/20 | 0.54 |
| ▸ | CCND3 | P30281 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25665799 | 1.00 | CCNE1 (0.54) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477913 | 0.98 | CCNE1 (0.56) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477878 | 0.98 | CCNE1 (0.56) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477891 | 0.98 | CCNE1 (0.56) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477803 | 0.97 | CDK2 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477880 | 0.97 | CDK2 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477893 | 0.97 | CDK2 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477804 | 0.89 | CDK2 (0.47) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477968 | 0.89 | CDK2 (0.47) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL24477970 | 0.89 | CDK2 (0.47) | CCNE1CDK2CCND1CDK6CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093769-A1 | AMINOHETEROARYL KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO.,LTD. (CN) | 2023-06-01 | — | — | WO | disclosed |
| WO-2022111621-A1 | AMINOHETEROARYL KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2022-06-02 | — | — | WO | disclosed |