Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 20/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.51 |
| ▸ | CCND1 | P24385 | 5/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.49 |
| ▸ | CDK1 | P06493 | 4/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND3 | P30281 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.41 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24477887 | 1.00 | CDK2 (0.51) | CDK2CCNE1CCND1CDK6CDK1 | |
| SCHEMBL25665857 | 0.91 | CDK2 (0.52) | CDK2CCNE1CCND1CDK6CDK1 | |
| SCHEMBL26942215 | 0.86 | CDK2 (0.51) | CDK2CCNE1CCND1CDK6CDK1 | |
| SCHEMBL26942213 | 0.86 | CDK2 (0.51) | CDK2CCNE1CCND1CDK6CDK1 | |
| SCHEMBL26942216 | 0.86 | CDK2 (0.51) | CDK2CCNE1CCND1CDK6CDK1 | |
| SCHEMBL26942269 | 0.86 | CDK2 (0.51) | CDK2CCNE1CCND1CDK6CDK1 | |
| SCHEMBL24477892 | 0.85 | CCNE1 (0.49) | CDK2CCNE1CCND1CDK6CCNT1 | |
| SCHEMBL24477652 | 0.85 | CCNE1 (0.49) | CDK2CCNE1CCND1CDK6CCNT1 | |
| SCHEMBL24477786 | 0.85 | CCNE1 (0.49) | CDK2CCNE1CCND1CDK6CCNT1 | |
| SCHEMBL26942929 | 0.77 | CDK2 (0.57) | CDK2CCNE1CCND1CDK6CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093769-A1 | AMINOHETEROARYL KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO.,LTD. (CN) | 2023-06-01 | — | — | WO | disclosed |
| WO-2022111621-A1 | AMINOHETEROARYL KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2022-06-02 | — | — | WO | disclosed |