Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 19/20 | 0.55 |
| ▸ | CDK2 | P24941 | 19/20 | 0.55 |
| ▸ | CDK1 | P06493 | 7/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.55 |
| ▸ | CCND1 | P24385 | 10/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 10/20 | 0.51 |
| ▸ | CDK4 | P11802 | 6/20 | 0.49 |
| ▸ | CCND3 | P30281 | 6/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24478200 | 1.00 | CCNE1 (0.55) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24478187 | 1.00 | CCNE1 (0.55) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24477867 | 0.93 | CCNE1 (0.54) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL29631731 | 0.93 | CCNE1 (0.54) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24477866 | 0.93 | CCNE1 (0.54) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24478193 | 0.93 | CCNE1 (0.54) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24477710 | 0.88 | CDK2 (0.54) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24477667 | 0.88 | CDK2 (0.54) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24477682 | 0.88 | CDK2 (0.54) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24478195 | 0.85 | CDK2 (0.50) | CCNE1CDK2CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111621-A1 | AMINOHETEROARYL KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2022-06-02 | — | — | WO | disclosed |