Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13213517 | 0.82 | CA1 (0.55) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL29630973 | 0.82 | CA1 (0.54) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL20732042 | 0.82 | CA1 (0.54) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL31269548 | 0.81 | CA1 (0.48) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL30061512 | 0.78 | CA1 (0.54) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL20732046 | 0.78 | CA1 (0.54) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL13213518 | 0.78 | CA1 (0.54) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL17549529 | 0.77 | CA1 (0.61) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL30968514 | 0.77 | CA1 (0.61) | CA1CA2ACHETSHRALDH1A1 | |
| SCHEMBL23938186 | 0.77 | CA1 (0.61) | CA1CA2ACHETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490506-A | Fused tricyclic compounds, process for their preparation and their use in medicine | 江苏恒瑞医药股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| WO-2022111636-A1 | FUSED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |