Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291548 | 0.94 | CRBN (0.46) | CRBNDDB1PDK2GPR119 | |
| SCHEMBL24299447 | 0.93 | CRBN (0.55) | CRBNDDB1PDK2GPR119 | |
| SCHEMBL24299444 | 0.87 | CRBN (0.54) | CRBNDDB1PDK2GPR119 | |
| SCHEMBL22951135 | 0.86 | CRBN (0.48) | CRBNDDB1PDK2GPR119 | |
| SCHEMBL22346841 | 0.85 | CRBN (0.63) | CRBNDDB1 | |
| SCHEMBL20046318 | 0.85 | CRBN (0.54) | CRBNDDB1PDK2GPR119 | |
| SCHEMBL29942851 | 0.85 | CRBN (0.63) | CRBNDDB1 | |
| SCHEMBL22498388 | 0.83 | CRBN (0.52) | CRBNDDB1 | |
| SCHEMBL31726811 | 0.83 | CRBN (0.52) | CRBNDDB1 | |
| SCHEMBL22291619 | 0.83 | DDB1 (0.55) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |