Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 19/20 | 0.63 |
| ▸ | CDK4 | P11802 | 16/20 | 0.63 |
| ▸ | CCND3 | P30281 | 17/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 13/20 | 0.57 |
| ▸ | CDK1 | P06493 | 12/20 | 0.57 |
| ▸ | CDK2 | P24941 | 9/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 6/20 | 0.55 |
| ▸ | PIM1 | P11309 | 4/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.54 |
| ▸ | CDK7 | P50613 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | CCNH | P51946 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683999 | 1.00 | CDK6 (0.63) | CDK6CDK4CCND3CCNA2CDK1 | |
| Hydrochloric Acid SCHEMBL29683933 | 0.99 | CDK6 (0.62) | CDK6CDK4CCND3CCNA2CDK1 | |
| SCHEMBL29684256 | 0.89 | CDK6 (0.67) | CDK6CDK4CCND3CCNA2CDK1 | |
| SCHEMBL24483440 | 0.89 | CDK6 (0.67) | CDK6CDK4CCND3CCNA2CDK1 | |
| SCHEMBL24483254 | 0.89 | CDK6 (0.56) | CDK6CDK4CCND3CCNA2CDK1 | |
| SCHEMBL29683930 | 0.89 | CDK6 (0.56) | CDK6CDK4CCND3CCNA2CDK1 | |
| Hydrochloric Acid SCHEMBL29684387 | 0.89 | CDK6 (0.66) | CDK6CDK4CCND3CCNA2CDK1 | |
| Hydrochloric Acid SCHEMBL29684272 | 0.88 | CDK6 (0.55) | CDK6CDK4CCND3CCNA2CDK1 | |
| SCHEMBL24482652 | 0.88 | CDK6 (0.67) | CDK6CDK4CCND3CCNA2CDK1 | |
| SCHEMBL29684372 | 0.88 | CDK6 (0.67) | CDK6CDK4CCND3CCNA2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |