Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 19/20 | 0.63 |
| ▸ | CCND3 | P30281 | 16/20 | 0.63 |
| ▸ | CDK4 | P11802 | 14/20 | 0.63 |
| ▸ | CDK2 | P24941 | 8/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.62 |
| ▸ | CDK1 | P06493 | 8/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.62 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.62 |
| ▸ | CCND1 | P24385 | 7/20 | 0.62 |
| ▸ | PIM1 | P11309 | 3/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684587 | 1.00 | CDK6 (0.63) | CDK6CCND3CDK4CDK2CDK5 | |
| SCHEMBL24483279 | 0.92 | CDK6 (0.62) | CDK6CCND3CDK4CDK2CDK5 | |
| SCHEMBL29684276 | 0.92 | CDK6 (0.62) | CDK6CCND3CDK4CDK2CDK5 | |
| Hydrochloric Acid SCHEMBL29684266 | 0.92 | CDK6 (0.61) | CDK6CCND3CDK4CDK2CDK5 | |
| SCHEMBL29684594 | 0.91 | CDK6 (0.52) | CDK6CCND3CDK4CDK2CDK5 | |
| SCHEMBL24483293 | 0.91 | CDK6 (0.52) | CDK6CCND3CDK4CDK2CDK5 | |
| SCHEMBL24483291 | 0.90 | CDK6 (0.54) | CDK6CCND3CDK4CDK2CDK5 | |
| SCHEMBL29684620 | 0.90 | CDK6 (0.54) | CDK6CCND3CDK4CDK2CDK5 | |
| SCHEMBL24483424 | 0.88 | CDK6 (0.59) | CDK6CCND3CDK4CDK2CDK5 | |
| SCHEMBL29683926 | 0.88 | CDK6 (0.59) | CDK6CCND3CDK4CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |