Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | SLC26A4 | O43511 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629850 | 1.00 | GAA (0.42) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL24485638 | 0.96 | GAA (0.41) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL29629771 | 0.96 | GAA (0.41) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL24484526 | 0.95 | GAA (0.44) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL29630128 | 0.93 | GAA (0.43) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL24485715 | 0.93 | GAA (0.43) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL29630100 | 0.92 | GAA (0.44) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL24485636 | 0.92 | GAA (0.44) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL24484527 | 0.88 | GAA (0.42) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL24484395 | 0.87 | GAA (0.41) | GAACASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |