Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26553767 | 1.00 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1ADORA3TAAR1 | |
| SCHEMBL24487848 | 0.93 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1ADORA3TAAR1 | |
| SCHEMBL26553761 | 0.93 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1ADORA3TAAR1 | |
| SCHEMBL4343382 | 0.89 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ADORA3TAAR1 | |
| SCHEMBL13626739 | 0.89 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ADORA3TAAR1 | |
| SCHEMBL13625827 | 0.89 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ADORA3TAAR1 | |
| SCHEMBL1582579 | 0.87 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1ADORA3ADORA2A | |
| SCHEMBL3315671 | 0.87 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1ADORA3ADORA2A | |
| SCHEMBL1582583 | 0.87 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1ADORA3ADORA2A | |
| SCHEMBL26553755 | 0.87 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365970-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230332153-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-11549110-B2 | Modified short interfering nucleic acid (siNA) molecules and uses thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20220177888-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365970-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | NSUN2, SNRPA, SNRPF | KDM4E 3173/4885TAS1R3 4267/4885TAS1R1 4293/4885 |
| US-11549110-B2 | Modified short interfering nucleic acid (siNA) molecules and uses thereof | NSUN2, SNRPA, SNRPF | KDM4E 3173/4885TAS1R3 4267/4885TAS1R1 4293/4885 |
| US-20220177888-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | NSUN2, SNRPA, SNRPF | KDM4E 3173/4885TAS1R3 4267/4885TAS1R1 4293/4885 |
| US-20230332153-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | NSUN2, SNRPA, SNRPF | KDM4E 3173/4885TAS1R3 4267/4885TAS1R1 4293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.