Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC3 | Q13489 | 13/20 | 0.47 |
| ▸ | XIAP | P98170 | 12/20 | 0.47 |
| ▸ | TNF | P01375 | 8/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24067350 | 1.00 | BIRC3 (0.47) | BIRC3XIAPTNFCNR1 | |
| SCHEMBL22450652 | 1.00 | BIRC3 (0.47) | BIRC3XIAPTNFCNR1 | |
| SCHEMBL22450678 | 1.00 | BIRC3 (0.47) | BIRC3XIAPTNFCNR1 | |
| SCHEMBL24488623 | 0.88 | BIRC3 (0.50) | BIRC3XIAPTNFCNR1 | |
| SCHEMBL24488641 | 0.88 | CNR1 (0.39) | BIRC3XIAPCNR1 | |
| SCHEMBL24067462 | 0.87 | XIAP (0.36) | BIRC3XIAPTNFCNR1 | |
| SCHEMBL24488639 | 0.86 | CNR1 (0.41) | CNR1 | |
| SCHEMBL24182198 | 0.84 | TNF (0.53) | BIRC3XIAPTNFCNR1 | |
| SCHEMBL22450711 | 0.84 | TNF (0.53) | BIRC3XIAPTNFCNR1 | |
| SCHEMBL22450736 | 0.84 | TNF (0.53) | BIRC3XIAPTNFCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175917-A1 | COMBINATION OF IAP INHIBITOR AND IMMUNE CHECKPOINT INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175917-A1 | COMBINATION OF IAP INHIBITOR AND IMMUNE CHECKPOINT INHIBITOR | BIRC5, XIAP, BIRC2 | BIRC3 4/4885XIAP 2/4885TNF 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.