Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 7/20 | 0.71 |
| ▸ | CDK4 | P11802 | 3/20 | 0.62 |
| ▸ | CCND1 | P24385 | 3/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | TNKS | O95271 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24489124 | 0.85 | GUSB (0.66) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL31238611 | 0.84 | GUSB (1.00) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL16007517 | 0.84 | GUSB (1.00) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL23743167 | 0.81 | GUSB (0.75) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL16018033 | 0.78 | GUSB (0.80) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL15690419 | 0.77 | GUSB (0.80) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL15691348 | 0.76 | CYP1A1 (1.00) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL15690958 | 0.76 | GUSB (1.00) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL16017996 | 0.74 | GUSB (0.76) | GUSBCDK4CCND1CYP1A1CYP1B1 | |
| SCHEMBL17786541 | 0.74 | GUSB (0.71) | GUSBCDK4CCND1CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |