Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | ROR1 | Q01973 | 4/20 | 0.46 |
| ▸ | ABL1 | P00519 | 15/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27897224 | 0.90 | CSF1R (0.47) | CSF1RROR1ABL1 | |
| SCHEMBL10207631 | 0.82 | MKNK1 (0.44) | CSF1RROR1ABL1 | |
| SCHEMBL17471695 | 0.79 | ABL1 (0.53) | CSF1RROR1ABL1 | |
| SCHEMBL16201026 | 0.78 | ABL1 (0.53) | CSF1RROR1ABL1 | |
| SCHEMBL22369939 | 0.75 | MKNK1 (0.46) | CSF1RROR1ABL1 | |
| SCHEMBL17471694 | 0.75 | ABL1 (0.53) | CSF1RROR1ABL1 | |
| SCHEMBL15096062 | 0.73 | ROR1 (0.67) | CSF1RROR1ABL1CYP3A4KCNH2 | |
| SCHEMBL29506341 | 0.73 | CSF1R (0.67) | CSF1RROR1ABL1CYP3A4KCNH2 | |
| SCHEMBL22243490 | 0.72 | CSF1R (0.66) | CSF1RROR1ABL1CYP3A4KCNH2 | |
| SCHEMBL29493472 | 0.72 | CSF1R (0.66) | CSF1RROR1ABL1CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120118-A1 | NOVEL RIPK1 KINASE TARGETING PROTACS AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2022-06-09 | — | — | WO | disclosed |