Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22804667 | 0.74 | SLC6A2 (0.45) | MEN1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL23602982 | 0.66 | SLC6A2 (0.38) | SLC6A2SLC6A4DRD2DRD4 | |
| SCHEMBL22804789 | 0.65 | MEN1 (0.37) | MEN1SLC6A2SLC6A4 | |
| SCHEMBL26101451 | 0.64 | SLC6A2 (0.43) | SLC6A2SLC6A4 | |
| SCHEMBL26103184 | 0.64 | SLC6A2 (0.43) | SLC6A2SLC6A4 | |
| SCHEMBL23602979 | 0.64 | ESRRB (0.52) | MEN1 | |
| SCHEMBL2046676 | 0.61 | SLC6A2 (0.49) | SLC6A2SLC6A4DRD2DRD4 | |
| SCHEMBL27160034 | 0.60 | SLC6A2 (0.55) | SLC6A2SLC6A4DRD2DRD4 | |
| SCHEMBL24319216 | 0.59 | SLC6A2 (0.47) | SLC6A2SLC6A4DRD2DRD4 | |
| SCHEMBL8271204 | 0.58 | SLC6A2 (0.36) | MEN1SLC6A2SLC6A4DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117487-A1 | NEW INDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-09 | — | — | WO | disclosed |