Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995692 | 0.81 | KMT2A (0.42) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL996384 | 0.80 | CA1 (0.46) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL14543044 | 0.75 | CYP2C19 (0.36) | CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL24496370 | 0.75 | CA1 (0.37) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL995693 | 0.74 | CA1 (0.47) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL23581682 | 0.74 | CA1 (0.56) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL22633330 | 0.74 | SLC1A3 (0.38) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL9592045 | 0.73 | CA1 (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL4411610 | 0.73 | SLC1A3 (0.40) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL4409728 | 0.73 | SLC1A3 (0.40) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177885-A1 | ENDOSOMAL CLEAVABLE LINKERS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-06-09 | — | — | US | disclosed |