Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 10/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 9/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586825 | 1.00 | CYP4A11 (0.61) | CYP4A11CYP4F2CYP2D6OPRK1NFKB1 | |
| SCHEMBL29588356 | 1.00 | CYP4A11 (0.61) | CYP4A11CYP4F2CYP2D6OPRK1NFKB1 | |
| SCHEMBL20730255 | 0.88 | CYP4F2 (0.79) | CYP4A11CYP4F2S1PR1S1PR3FFAR1 | |
| SCHEMBL5847508 | 0.84 | CYP4F2 (0.61) | CYP4A11CYP4F2CYP2D6OPRK1NFKB1 | |
| SCHEMBL6529352 | 0.84 | CYP4F2 (0.61) | CYP4A11CYP4F2CYP2D6OPRK1NFKB1 | |
| Hydrochloric Acid SCHEMBL5847506 | 0.83 | CYP4F2 (0.60) | CYP4A11CYP4F2CYP2D6OPRK1NFKB1 | |
| Hydrochloric Acid SCHEMBL6529351 | 0.83 | CYP4F2 (0.60) | CYP4A11CYP4F2CYP2D6OPRK1NFKB1 | |
| Hydrochloric Acid SCHEMBL5847504 | 0.83 | CYP4F2 (0.60) | CYP4A11CYP4F2CYP2D6OPRK1NFKB1 | |
| SCHEMBL24496642 | 0.83 | CYP4F2 (0.51) | CYP4A11CYP4F2S1PR1S1PR3PPARG | |
| SCHEMBL22070572 | 0.81 | CYP4F2 (0.82) | CYP4A11CYP4F2S1PR1S1PR3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120048-A1 | HDAC INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-06-09 | — | — | WO | disclosed |