SCHEMBL2449743

SCHEMBL2449743

CCCCCCCCCCCCCC(CSCCC(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.53
GRIK2 Q13002 2/20 0.53
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
FFAR4 Q5NUL3 2/20 0.49
FFAR1 O14842 2/20 0.49
PLA2G4B P0C869 1/20 0.47
FOLH1 Q04609 1/20 0.46
CA2 P00918 1/20 0.46
MAPK1 P28482 1/20 0.46
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 6/20 0.46
PPARD Q03181 6/20 0.46
PPARA Q07869 6/20 0.46
HDAC11 Q96DB2 5/20 0.46
TSHR P16473 4/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8379986 1.00 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1FFAR4
SCHEMBL2479660 1.00 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1FFAR4
SCHEMBL2480793 1.00 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1FFAR4
SCHEMBL8469261 1.00 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1FFAR4
SCHEMBL2478415 1.00 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1FFAR4
E388 SCHEMBL31317498 0.98 GRIK1 (0.51) GRIK1GRIK2SLC1A2SLC1A1FFAR4
SCHEMBL4539291 0.98 GRIK1 (0.51) GRIK1GRIK2SLC1A2SLC1A1FFAR4
SCHEMBL9069126 0.94 FOLH1 (0.51) GRIK1GRIK2SLC1A2SLC1A1FFAR4
SCHEMBL9008368 0.92 PPARG (0.54) FFAR4FFAR1PPARGPPARDPPARA
SCHEMBL9108768 0.88 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1354003-B1 THERMOPLASTIC SILICONE ELASTOMERS FORMED FROM POLYESTER RESINS DOW CORNING (US) 2004-09-29 EP claimed
CN-103348494-B connecting structure for solar power generation module 旭化成株式会社 2016-09-07 CN disclosed
CN-105609193-A Electric wire and cable HITACHI METALS LTD 2016-05-25 CN disclosed
CN-105609166-A Electric wire and cable HITACHI METALS LTD 2016-05-25 CN disclosed
US-8017673-B2 Polymer stabilizer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-13 US disclosed
US-20100179253-A1 POLYMER STABILIZER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-15 US disclosed
US-20100179264-A1 POLYMER STABILIZER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-15 US disclosed
EP-2206740-A2 Polymer stabilizer Sumitomo Chemical Company, Limited (JP) 2010-07-14 EP disclosed
EP-2206739-A2 Polymer stabilizer Sumitomo Chemical Company, Limited (JP) 2010-07-14 EP disclosed
EP-0246190-A2 Derivatives of isocyanuric acid CIBA-GEIGY AG (CH) 1987-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179264-A1 POLYMER STABILIZER CCNA1, CCNH, NAP1L1 GRIK1 3073/4885GRIK2 2684/4885SLC1A2 4551/4885
US-20100179253-A1 POLYMER STABILIZER CNOT1, PARP1, FKBP1B GRIK1 3972/4885GRIK2 4265/4885SLC1A2 4836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.