SCHEMBL2449749

SCHEMBL2449749

CCCCCCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OCCCCCC)cc3)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.81
LMNA P02545 3/20 0.81
NFKB1 P19838 3/20 0.81
NFKB2 Q00653 3/20 0.81
RELA Q04206 3/20 0.81
SMN1; SMN2 Q16637 2/20 0.81
CYP1A2 P05177 1/20 0.78
CYP3A4 P08684 1/20 0.78
CYP2D6 P10635 1/20 0.78
CYP2C9 P11712 1/20 0.78
CYP2C19 P33261 1/20 0.78
TP53 P04637 1/20 0.71
TSHR P16473 1/20 0.71
PLA2G4B P0C869 5/20 0.69
MAPT P10636 2/20 0.68
POLB P06746 1/20 0.68
PRSS1 P07477 1/20 0.68
ACR P10323 1/20 0.68
KMT2A Q03164 2/20 0.67
RARB P10826 3/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9817742 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL5384727 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL2455384 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL12732828 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL9403669 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL7875559 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL9457697 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL22341180 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL21084422 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA
SCHEMBL9512630 1.00 NPC1 (0.81) NPC1LMNANFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
US-20170336663-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2017-11-23 US disclosed
EP-3215587-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF Gauzy Ltd. (IL) 2017-09-13 EP disclosed
EP-0656927-B1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S C P A (IT) 1999-12-01 EP disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 EP disclosed
US-5843333-A Metallo organo liquid crystals in a polymer matrix SNIARICERCHE S.C.P.A (IT) 1998-12-01 US disclosed
EP-0803525-A2 Chiral anisotropic thermosets (cat) in polymer stabilized liquid crystals Sniaricerche S.C.P.A. (IT) 1997-10-29 EP disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 EP disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed
EP-0656927-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX Sniaricerche S.C.P.A. (IT) 1995-06-14 EP disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 WO disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed