SCHEMBL24498024

SCHEMBL24498024

COc1c(N)cc(F)cc1-c1cnc(C(C)C)cn1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 18/20 0.42
ALOX5AP P20292 17/20 0.42
FYN P06241 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29686449 1.00 FEN1 (0.42) FEN1ALOX5APFYN
SCHEMBL24498204 0.82 ALOX5AP (0.42) FEN1ALOX5APFYN
SCHEMBL29686853 0.82 ALOX5AP (0.42) FEN1ALOX5APFYN
SCHEMBL26512731 0.82 ALOX5AP (0.35) FEN1ALOX5AP
SCHEMBL28838931 0.79 ALOX5AP (0.34) FEN1ALOX5AP
SCHEMBL30740055 0.78 FEN1 (0.45) FEN1ALOX5AP
SCHEMBL27172758 0.78 FEN1 (0.45) FEN1ALOX5AP
SCHEMBL24498032 0.78 FEN1 (0.44) FEN1ALOX5AP
SCHEMBL29686208 0.78 FEN1 (0.44) FEN1ALOX5AP
SCHEMBL26119323 0.77 TYK2 (0.34) FEN1ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240101548-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD (CN) 2024-03-28 US disclosed
EP-4257587-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2023-10-11 EP disclosed
WO-2022117016-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 深圳微芯生物科技股份有限公司 2022-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101548-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF TYK2, WEE2, WEE1 FEN1 3616/4885ALOX5AP 1962/4885FYN 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.