Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.58 |
| ▸ | JAK1 | P23458 | 13/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684783 | 0.92 | TYK2 (0.55) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24497531 | 0.92 | TYK2 (0.55) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL29685507 | 0.91 | TYK2 (0.57) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24497530 | 0.91 | TYK2 (0.57) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24498215 | 0.90 | TYK2 (0.56) | TYK2JAK1JAK2KCNH2 | |
| SCHEMBL29684989 | 0.90 | TYK2 (0.56) | TYK2JAK1JAK2KCNH2 | |
| SCHEMBL26523264 | 0.89 | TYK2 (0.48) | TYK2JAK1JAK2KCNH2 | |
| SCHEMBL30724620 | 0.89 | TYK2 (0.64) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24498344 | 0.89 | TYK2 (0.64) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24497655 | 0.88 | TYK2 (0.63) | TYK2JAK1JAK2JAK3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257587-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |