⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23229576 | 0.70 | — | — | |
| SCHEMBL18610801 | 0.68 | — | — | |
| SCHEMBL23917941 | 0.64 | — | — | |
| SCHEMBL24498715 | 0.56 | — | — | |
| SCHEMBL1987803 | 0.55 | — | — | |
| SCHEMBL14927155 | 0.50 | — | — | |
| SCHEMBL13012535 | 0.49 | — | — | |
| SCHEMBL4577180 | 0.44 | — | — | |
| SCHEMBL16817229 | 0.44 | — | — | |
| SCHEMBL12996755 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177462-A1 | SUBSTITUTED HETEROCYCLIC AMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2022-06-09 | — | — | US | disclosed |