SCHEMBL24499393

SCHEMBL24499393

CCC(c1ccc2sc(C)nc2c1)N1CCN(c2ncc(C)cn2)CC1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OGA O60502 19/20 0.59
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24499335 0.87 OGA (0.76) OGA
SCHEMBL21764666 0.79 OGA (0.67) OGA
SCHEMBL17551373 0.78 OGA (0.73) OGA
SCHEMBL21764475 0.77 OGA (0.65) OGA
SCHEMBL21764423 0.77 OGA (0.71) OGA
SCHEMBL24499385 0.77 OGA (0.54) OGA
SCHEMBL25682831 0.76 OGA (0.71) OGA
SCHEMBL21764665 0.76 OGA (0.84) OGA
SCHEMBL20760259 0.75 OGA (0.87) OGA
SCHEMBL25901904 0.75 OGA (0.68) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220177470-A1 SULFOXIMINE GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177470-A1 SULFOXIMINE GLYCOSIDASE INHIBITORS ENGASE, BACE1, GAA OGA 57/4885HSD17B10 1024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.