Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695079 | 1.00 | POLQ (0.72) | POLQ | |
| SCHEMBL29108327 | 0.92 | POLQ (0.70) | POLQ | |
| SCHEMBL29694701 | 0.92 | POLQ (0.70) | POLQ | |
| SCHEMBL29108165 | 0.92 | POLQ (0.69) | POLQ | |
| SCHEMBL29694922 | 0.92 | POLQ (0.69) | POLQ | |
| SCHEMBL29108393 | 0.92 | POLQ (0.64) | POLQ | |
| SCHEMBL29694956 | 0.92 | POLQ (0.64) | POLQ | |
| SCHEMBL29108533 | 0.91 | POLQ (0.68) | POLQ | |
| SCHEMBL29694977 | 0.91 | POLQ (0.68) | POLQ | |
| SCHEMBL29694767 | 0.91 | POLQ (0.72) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083271-A | Substituted thiadiazolyl derivatives as DNA polymerase theta inhibitors | 伊迪亚生物科学有限公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2022118210-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-06-09 | — | — | WO | disclosed |