Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282440 | 0.83 | PPM1D (0.41) | PPM1D | |
| SCHEMBL12246566 | 0.75 | PPM1D (0.35) | PPM1D | |
| SCHEMBL16516673 | 0.74 | PPM1D (0.33) | PPM1D | |
| SCHEMBL2376304 | 0.74 | PPM1D (0.40) | PPM1D | |
| SCHEMBL2279233 | 0.72 | PPM1D (0.33) | PPM1D | |
| SCHEMBL646479 | 0.71 | PPM1D (0.43) | PPM1D | |
| SCHEMBL15115825 | 0.71 | PPM1D (0.38) | PPM1D | |
| SCHEMBL7335164 | 0.71 | PPM1D (0.35) | PPM1D | |
| SCHEMBL31561768 | 0.70 | — | — | |
| SCHEMBL20087739 | 0.70 | PPM1D (0.40) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118210-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-06-09 | — | — | WO | disclosed |