Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24499623 | 1.00 | POLQ (0.66) | POLQ | |
| SCHEMBL29694787 | 1.00 | POLQ (0.66) | POLQ | |
| SCHEMBL29694614 | 0.96 | POLQ (0.60) | POLQ | |
| SCHEMBL24501159 | 0.96 | POLQ (0.60) | POLQ | |
| SCHEMBL24500951 | 0.96 | POLQ (0.67) | POLQ | |
| SCHEMBL24500855 | 0.96 | POLQ (0.68) | POLQ | |
| SCHEMBL29694749 | 0.92 | POLQ (0.62) | POLQ | |
| SCHEMBL24501355 | 0.91 | POLQ (0.61) | POLQ | |
| SCHEMBL24770848 | 0.90 | POLQ (0.73) | POLQ | |
| SCHEMBL24770125 | 0.90 | POLQ (0.72) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118210-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-06-09 | — | — | WO | disclosed |