Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629002 | 0.88 | HSD17B10 (0.38) | CHRM2CHRM1CHRM3HDAC8HSD17B10 | |
| SCHEMBL629003 | 0.88 | HSD17B10 (0.38) | CHRM2CHRM1CHRM3HDAC8HSD17B10 | |
| SCHEMBL15776484 | 0.86 | CHRM2 (0.36) | CHRM2CHRM1CHRM3HDAC8HSD17B10 | |
| SCHEMBL15776483 | 0.86 | CHRM2 (0.36) | CHRM2CHRM1CHRM3HDAC8HSD17B10 | |
| SCHEMBL12333016 | 0.85 | HRH3 (0.33) | MAPK1 | |
| SCHEMBL14570223 | 0.83 | HDAC8 (0.32) | CHRM2CHRM1CHRM3HDAC8 | |
| SCHEMBL14596798 | 0.83 | HDAC8 (0.32) | CHRM2CHRM1CHRM3HDAC8 | |
| SCHEMBL5371275 | 0.80 | KMT2A (0.40) | HDAC8SMN1; SMN2 | |
| SCHEMBL5371270 | 0.80 | KMT2A (0.40) | HDAC8SMN1; SMN2 | |
| SCHEMBL25365058 | 0.80 | ELANE (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107877-A2 | COMPOUNDS AND COMPOSITIONS AND THEIR USE IN THE TREATMENT OF DISEASES RELATED TO COPPER RETENTION | KANDULA MAHESH (IN) | 2011-09-09 | — | — | WO | disclosed |