Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11852682 | 0.83 | SMN1; SMN2 (0.43) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11852690 | 0.83 | SMN1; SMN2 (0.43) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20886628 | 0.80 | SMN1; SMN2 (0.41) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14433706 | 0.77 | POLB (0.54) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10739509 | 0.77 | POLB (0.54) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL174303 | 0.77 | POLB (0.54) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31737192 | 0.77 | POLB (0.54) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10739512 | 0.77 | POLB (0.54) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL60588 | 0.77 | POLB (0.54) | POLBTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12484369 | 0.75 | CYP1A2 (0.39) | POLBALDH1A1SMN1; SMN2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220187707-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING ALICYCLIC COMPOUND-TERMINATED POLYMER | NISSAN CHEMICAL CORPORATION (JP) | 2022-06-16 | — | — | US | disclosed |