Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.65 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27078368 | 0.92 | TLR8 (0.63) | TLR8TLR7 | |
| SCHEMBL30807905 | 0.92 | TLR8 (0.63) | TLR8TLR7 | |
| SCHEMBL30945309 | 0.87 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL30945306 | 0.86 | TLR8 (0.75) | TLR8TLR7 | |
| SCHEMBL24512073 | 0.85 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL24507423 | 0.83 | TLR8 (0.73) | TLR8TLR7 | |
| SCHEMBL30601185 | 0.83 | TLR8 (0.68) | TLR8TLR7 | |
| SCHEMBL24507104 | 0.83 | TLR8 (0.50) | TLR8TLR7 | |
| SCHEMBL24507915 | 0.82 | TLR8 (0.49) | TLR8TLR7 | |
| SCHEMBL27078384 | 0.82 | TLR8 (0.69) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125908-A1 | ANTI-PD-L1 IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022125904-A1 | ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |