Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24508248 | 0.73 | TLR9 (0.38) | TLR9 | |
| SCHEMBL10153335 | 0.69 | GBA1 (0.49) | SLC6A2SLC6A4SLC6A3HTR1AGBA1 | |
| SCHEMBL24282016 | 0.68 | — | — | |
| SCHEMBL18849234 | 0.66 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3TMEM97SIGMAR1 | |
| SCHEMBL7545018 | 0.61 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL30174437 | 0.61 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL11105943 | 0.61 | TMEM97 (0.56) | SLC6A2SLC6A4SLC6A3TMEM97SIGMAR1 | |
| SCHEMBL873444 | 0.60 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL51254 | 0.60 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL2186411 | 0.60 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220186217-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-06-16 | — | — | US | disclosed |