Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6362760 | 0.92 | EGFR (0.87) | EGFRERBB2 | |
| SCHEMBL2443400 | 0.91 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL6359640 | 0.91 | EGFR (0.85) | EGFRERBB2 | |
| SCHEMBL2450733 | 0.91 | EGFR (0.85) | EGFRERBB2 | |
| SCHEMBL2445439 | 0.89 | EGFR (0.78) | EGFRERBB2 | |
| SCHEMBL2441624 | 0.89 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL2446787 | 0.88 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL2446264 | 0.87 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL2443974 | 0.87 | EGFR (0.93) | EGFRERBB2 | |
| SCHEMBL2447793 | 0.86 | EGFR (0.80) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446401-B1 | C5-modified indazolylpyrrolotriazines | BRISTOL MYERS SQUIBB CO (US) | 2011-09-14 | — | — | EP | disclosed |
| US-6908916-B2 | C-5 modified indazolylpyrrolotriazines | BRISTOL MYERS SQUIBB COMPANY (US) | 2005-06-21 | — | — | US | disclosed |