SCHEMBL2451

SCHEMBL2451

[CH]1CCCS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28134812 0.96
SCHEMBL28134797 0.96
SCHEMBL21082955 0.89
SCHEMBL27629238 0.87
SCHEMBL3547770 0.86
SCHEMBL3547450 0.86
SCHEMBL3548074 0.86
SCHEMBL421348 0.86
SCHEMBL416905 0.86
SCHEMBL28292185 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 107134 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
CN-118369335-A N1-modified pseudouridine and application thereof in mRNA synthesis 上海吉量医药工程有限公司 2024-07-19 CN claimed
WO-2024149340-A1 INDOLONE DERIVATIVE HAVING IRAK4 INHIBITORY ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳众格生物科技有限公司 2024-07-18 WO claimed
US-20240239775-A1 FXR REGULATOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF BEIJING BEST PATHWAY MANAGEMENT CONSULTING CENTER (LIMITED PARTNERSHIP) (CN) 2024-07-18 US claimed
EP-4399216-A1 IMMUNOMODULATING AZALIDES Zoetis Services LLC (US) 2024-07-17 EP claimed
EP-4399209-A1 NEW QUINOLINE DERIVATIVES Elanco Animal Health GmbH (DE) 2024-07-17 EP claimed
EP-4399204-A1 POTENT AND SELECTIVE INHIBITORS OF IRAK4 Dana-Farber Cancer Institute, Inc. (US) 2024-07-17 EP claimed
CN-115916777-B ATX inhibitor and preparation method and application thereof 苏州爱科百发生物医药技术有限公司 2024-07-12 CN claimed
WO-2024147306-A1 AMIDE COMPOUND AND HARMFUL ARTHROPOD CONTROL COMPOSITION CONTAINING SAME 住友化学株式会社 2024-07-11 WO claimed
WO-2024146627-A1 MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 北京清辉联诺生物科技有限责任公司 2024-07-11 WO claimed
EP-0010673-A2 Substituted N-propargyl anilines, process for their preparation and their use as fungicides BAYER AG (DE) 1980-05-14 EP claimed
US-4199590-A Piperidino ureas and thioureas JOHN WYETH & BROTHER LIMITED (GB) 1980-04-22 US claimed
US-4193926-A 4-(Polyalkoxy phenyl)-2-pyrrolidones SCHERING AKTIENGESELLSCHAFT (DE) 1980-03-18 US claimed
US-4179557-A Acylation of 7-aminocephalosporanic acids PRESIDENT OF OSAKA UNIVERSITY (JP) 1979-12-18 US claimed
US-4156729-A ANTITHROMBOTIC BAYER AKTIENGESELLSCHAFT (DE) 1979-05-29 US claimed
US-4123611-A N-protected amino compounds PRESIDENT OF OSAKA UNIVERSITY (JP) 1978-10-31 US claimed
US-4112113-A ANTIARTHRITIC SMITHKLINE CORPORATION (US) 1978-09-05 US claimed
US-4101541-A DYES FOR POLYESTERS OR POLYPROPYLENE CIBA-GEIGY CORPORATION (US) 1978-07-18 US claimed
US-4036710-A FROM AN ACIDIC BATH CONTAINING A BASIC DI- OR TRI-AMINO-TRIARYLMETHANE DYE AND A SULFOALKYL SULFIDE M & T CHEMICALS INC. (US) 1977-07-19 US claimed
US-3980609-A ANTHRAPYRIDONE DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US claimed