Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 20/20 | 0.72 |
| ▸ | BAZ2A | Q9UIF9 | 19/20 | 0.72 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.71 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.62 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.62 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.62 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19586201 | 0.84 | BAZ2B (0.77) | BAZ2BBAZ2ABRD9TRIM24TAF1L | |
| SCHEMBL29613447 | 0.84 | BAZ2B (0.77) | BAZ2BBAZ2ABRD9TRIM24TAF1L | |
| SCHEMBL23318444 | 0.84 | BAZ2B (0.79) | BAZ2BBAZ2ABRD9TRIM24TAF1L | |
| SCHEMBL24510745 | 0.81 | BAZ2B (1.00) | BAZ2BBAZ2ABRD9TRIM24TAF1L | |
| SCHEMBL29352262 | 0.77 | BAZ2B (1.00) | BAZ2BBAZ2ABRD9TRIM24TAF1L | |
| SCHEMBL22339997 | 0.77 | BAZ2B (1.00) | BAZ2BBAZ2ABRD9TRIM24TAF1L | |
| SCHEMBL20805573 | 0.68 | BAZ2B (0.79) | BAZ2BBAZ2ABRD9TRIM24TAF1L | |
| SCHEMBL12545613 | 0.64 | KMT2A (0.49) | — | |
| SCHEMBL19697982 | 0.64 | ALOX5AP (0.41) | BAZ2BBAZ2ABRD9 | |
| SCHEMBL13889409 | 0.61 | MCL1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023219939-A1 | COMPOUNDS AND METHODS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |