Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 2/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512359 | 1.00 | CNR1 (0.46) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL30899268 | 0.89 | CNR1 (0.43) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL24512244 | 0.89 | CNR1 (0.43) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL24512334 | 0.85 | CNR1 (0.48) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29717135 | 0.85 | CNR1 (0.48) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29717158 | 0.85 | CNR1 (0.41) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL24512243 | 0.85 | CNR1 (0.41) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29717111 | 0.84 | CNR1 (0.64) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL24512245 | 0.84 | CNR1 (0.64) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL24512122 | 0.83 | CNR2 (0.44) | CNR1CNR2MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125989-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | SCRIPPS RESEARCH INSTITUTE, THE (US) | 2022-06-16 | — | — | WO | disclosed |