SCHEMBL2451653

SCHEMBL2451653

CCOC(=O)C=Cc1ccc(N=Cc2ccc(OCC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
CYP3A4 P08684 1/20 0.53
MAOB P27338 9/20 0.52
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
TP53 P04637 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KMT2A Q03164 1/20 0.50
ABCG2 Q9UNQ0 1/20 0.49
TTR P02766 1/20 0.49
DPP4 P27487 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2451651 1.00 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL2451632 0.90 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL2451638 0.90 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL2451637 0.90 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL1959915 0.88 CA12 (0.71) CA12CA1CA2CA7CA9
SCHEMBL2043458 0.88 CA12 (0.71) CA12CA1CA2CA7CA9
SCHEMBL9556747 0.87 NPC1 (0.56) MAOBNPC1RAB9AMAPTKDM4E
SCHEMBL19460778 0.82 KMT2A (0.57) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL12416627 0.82 KMT2A (0.57) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL10278284 0.81 CA12 (0.69) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20150009456-A1 Polymer-stabilized thermotropic liquid crystal device ROSELLA HOLDINGS LIMITED (GG) 2015-01-08 US disclosed
US-8828176-B2 Polymer stabilized thermotropic liquid crystal device RAVENBRICK LLC (US) 2014-09-09 US disclosed
EP-2553520-A1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE Ravenbrick, LLC (US) 2013-02-06 EP disclosed
WO-2011123457-A1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2011-10-06 WO disclosed
US-20110234944-A1 Polymer-stabilized thermotropic liquid crystal device RAVENBRICK LLC (US) 2011-09-29 US disclosed
EP-0747461-B1 Polymer stabilized liquid crystals and flexible devices thereof SNIARICERCHE S C P A (IT) 2001-09-05 EP disclosed
US-6049366-A PLACING A LIQUID CRYSTAL FLUID COMPRISING LIQUID CRYSTAL, A PREPOLYMER, AND MICROPARTICLES BETWEEN FLEXIBLE CONDUCTIVE SUBSTRATES; LAMINATING THE SUBSTRATE TOGETHER, CURING THE FLUID LIQUID CRYSTAL COMPRISING THE PREPOLYMER SNIARICERCHE S.C.P.A. (IT) 2000-04-11 US disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 EP disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 EP disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-4038199-A LYOTROPIC NEMATIC LIQUID CRYSTALS FOR USE IN ELECTRO-OPTICAL DISPLAY DEVICES TEXAS INSTRUMENTS INCORPORATED (US) 1977-07-26 US disclosed
US-4038200-A LYOTROPIC NEMATIC LIQUID CRYSTALS FOR USE IN ELECTRO-OPTICAL DISPLAY DEVICES TEXAS INSTRUMENTS INCORPORATED (US) 1977-07-26 US disclosed
US-4035060-A Electro-optic device DAINIPPON PRINTING CO., LTD (JA) 1977-07-12 US disclosed
US-4005928-A Nematic liquid crystal displays for low voltage direct current operation TEXAS INSTRUMENTS INCORPORATED (US) 1977-02-01 US disclosed
US-3965030-A BENZYLIDENEAMINES TEXAS INSTRUMENTS INCORPORATED (US) 1976-06-22 US disclosed
US-3944330-A Electro-optic device DAINIPPON PRINTING CO., LTD. (JA) 1976-03-16 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed