Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727843 | 0.73 | MAPT (0.44) | CCNT1CDK9CYP2C19MTNR1APOLB | |
| SCHEMBL24518537 | 0.73 | MAPT (0.44) | CCNT1CDK9CYP2C19MTNR1APOLB | |
| SCHEMBL26794064 | 0.72 | MAPT (0.45) | CCNT1CDK9POLBLMNAMAPT | |
| SCHEMBL29727842 | 0.72 | MAPT (0.45) | CCNT1CDK9POLBLMNAMAPT | |
| SCHEMBL24518366 | 0.72 | FFAR1 (0.43) | CCNT1CDK9LMNAMAPTKDM4E | |
| SCHEMBL1305574 | 0.71 | MEN1 (0.60) | CYP2C19MTNR1APOLBMAPTKDM4E | |
| SCHEMBL27531911 | 0.71 | MEN1 (0.60) | CYP2C19MTNR1APOLBMAPTKDM4E | |
| SCHEMBL2379006 | 0.69 | MEN1 (0.62) | CYP2C19POLBMAPTKDM4ERECQL | |
| SCHEMBL29363142 | 0.68 | MEN1 (0.68) | CYP2C19POLBMAPTKDM4ERECQL | |
| SCHEMBL35884 | 0.68 | MEN1 (0.68) | CYP2C19POLBMAPTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820764-B2 | Compound modulating GSK-3 activity | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2023-11-21 | — | — | US | disclosed |
| US-20220185805-A1 | NOVEL COMPOUND MODULATING GSK-3 ACTIVITY | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185805-A1 | NOVEL COMPOUND MODULATING GSK-3 ACTIVITY | GSK3B, GSK3A, GSKIP | CCNT1 460/4885CDK9 137/4885CYP2C19 1572/4885 |
| US-11820764-B2 | Compound modulating GSK-3 activity | GSK3B, GSK3A, GSKIP | CCNT1 409/4885CDK9 102/4885CYP2C19 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.