Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.78 |
| ▸ | LCK | P06239 | 1/20 | 0.78 |
| ▸ | FYN | P06241 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5049555 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9525106 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9525105 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL8180631 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL11186790 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL21635193 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL4727091 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9523969 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL6832356 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL17503594 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126617-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KINASES VIA UBIQUITIN PROTEOSOME PATHWAY | CROSSFIRE ONCOLOGY HOLDING B.V. (NL) | 2024-06-20 | — | — | WO | disclosed |
| CN-118184667-A | Rhodamine-cyanine compound containing hydrazide, tautomer thereof, preparation method and application thereof | 浙江大学长三角智慧绿洲创新中心 | 2024-06-14 | — | — | CN | disclosed |
| CN-116694694-A | Enzyme catalysis process for preparing pregabalin chiral intermediate | 尚科生物医药（上海）有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-3615516-B1 | IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS | PASTEUR INSTITUT (FR) | 2021-11-17 | — | — | EP | disclosed |
| WO-2021065980-A1 | BET DEGRADER | 協和キリン株式会社 | 2021-04-08 | — | — | WO | disclosed |
| WO-2020189734-A1 | NOVEL COMPOUND, AND ENZYME INHIBITOR AND ABP COMPRISING RELATED NOVEL COMPOUND | 国立大学法人九州大学 | 2020-09-24 | — | — | WO | disclosed |
| EP-3615516-A1 | IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS | Institut Pasteur (FR) | 2020-03-04 | — | — | EP | disclosed |
| WO-2019196918-A1 | FIVE-MEMBERED HETEROCYCLO-PYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 罗欣药业(上海)有限公司 | 2019-10-17 | — | — | WO | disclosed |
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |
| WO-2019151384-A1 | RADIOACTIVE PHARMACEUTICAL | 国立大学法人千葉大学 | 2019-08-08 | — | — | WO | disclosed |
| EP-1071656-A1 | FLUOROVINYLOXYACETAMIDES, PROCESS FOR PREPARING SAME AND HERBICIDAL COMPOSITION COMPRISING SAME | Korea Research Institute of Chemical Technology (KR) | 2001-01-31 | — | — | EP | disclosed |
| EP-1029541-A1 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR GLOMERULOPATHY | SHIONOGI & CO., LTD. (JP) | 2000-08-23 | — | — | EP | disclosed |
| EP-0950656-A1 | SULFONATED AMINO ACID DERIVATIVES AND METALLOPROTEINASE INHIBITORS CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1999-10-20 | — | — | EP | disclosed |
| WO-1999047491-A1 | FLUOROVINYLOXYACETAMIDES, PROCESS FOR PREPARING SAME AND HERBICIDAL COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |
| EP-0514942-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1997-03-05 | — | — | EP | disclosed |
| EP-0514935-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-11-08 | — | — | EP | disclosed |
| EP-0514935-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0514942-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0015540-A2 | New triazene compound, process for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-09-17 | — | — | EP | disclosed |