Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 18/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 18/20 | 0.53 |
| ▸ | EIF4E | P06730 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620639 | 0.93 | MKNK1 (0.54) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL16625996 | 0.90 | MKNK1 (0.54) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL16621090 | 0.90 | MKNK1 (0.56) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL16621478 | 0.89 | MKNK1 (0.64) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL24520061 | 0.88 | MKNK1 (0.57) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL16620568 | 0.88 | MKNK1 (0.53) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL16620656 | 0.88 | MKNK1 (0.54) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL16621219 | 0.87 | MKNK1 (0.51) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL16625994 | 0.87 | MKNK1 (0.53) | MKNK1MKNK2EIF4ECYP3A4KCNH2 | |
| SCHEMBL16620666 | 0.87 | MKNK1 (0.53) | MKNK1MKNK2EIF4ECYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052501-B1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2022-06-22 | — | — | EP | disclosed |