Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 16/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 16/20 | 0.54 |
| ▸ | EIF4E | P06730 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620724 | 0.88 | MKNK1 (0.56) | MKNK1MKNK2EIF4ECYP3A4RET | |
| SCHEMBL19841342 | 0.87 | MKNK1 (0.63) | MKNK1MKNK2EIF4ECYP3A4 | |
| SCHEMBL16620678 | 0.87 | MKNK1 (0.68) | MKNK1MKNK2EIF4ECYP3A4RET | |
| SCHEMBL16620815 | 0.86 | MKNK1 (0.59) | MKNK1MKNK2EIF4ECYP3A4PARP1 | |
| SCHEMBL24520080 | 0.85 | FYN (0.37) | ABL1 | |
| SCHEMBL17969602 | 0.81 | MKNK1 (0.66) | MKNK1MKNK2EIF4ECYP3A4 | |
| SCHEMBL16625987 | 0.80 | MKNK1 (0.65) | MKNK1MKNK2EIF4ECYP3A4PARP1 | |
| SCHEMBL29756275 | 0.80 | MKNK1 (0.60) | MKNK1MKNK2EIF4ECYP3A4PARP1 | |
| SCHEMBL16620737 | 0.80 | MKNK1 (0.60) | MKNK1MKNK2EIF4ECYP3A4PARP1 | |
| SCHEMBL16620911 | 0.79 | MKNK1 (0.64) | MKNK1MKNK2EIF4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052501-B1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2022-06-22 | — | — | EP | disclosed |