SCHEMBL24521826

SCHEMBL24521826

Sc1ccc2cc(-c3ccccc3)ccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.57
ESR2 Q92731 6/20 0.57
BACE1 P56817 1/20 0.46
HSD17B1 P14061 2/20 0.45
HSD17B2 P37059 2/20 0.45
PGR P06401 1/20 0.44
NPC1 O15118 1/20 0.44
CYP11B1 P15538 2/20 0.43
CYP11B2 P19099 2/20 0.43
CYP17A1 P05093 1/20 0.42
CYP19A1 P11511 1/20 0.42
ALOX5 P09917 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2B6 P20813 1/20 0.42
CYP2C19 P33261 1/20 0.42
FGFR1 P11362 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16107069 0.85 ESR1 (0.73) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL30304006 0.85 ESR1 (0.73) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL14218405 0.84 ESR1 (0.61) ESR1ESR2HSD17B1HSD17B2NPC1
SCHEMBL27331721 0.81 ESR1 (0.53) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL29876034 0.80 ESR1 (0.70) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL275918 0.80 ESR1 (0.70) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL29429082 0.80 ESR1 (0.70) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL4946140 0.80 ESR1 (0.70) ESR1ESR2BACE1HSD17B1HSD17B2
Biphenyl SCHEMBL4007823 0.80 ESR1 (0.70) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL1527451 0.80 ESR1 (0.67) ESR1ESR2BACE1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230200227-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-22 US disclosed
EP-4016656-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2022-06-22 EP disclosed