Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PPM1B | O75688 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081295 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL3238065 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL12524610 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL18681189 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL16258710 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL14853797 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL14586081 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL12556245 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL21007945 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL16918612 | 1.00 | POLB (0.47) | POLBKMT2AMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015005-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | ModernaTX, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |