Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055011 | 0.92 | HDAC6 (0.72) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL8053546 | 0.86 | HDAC6 (0.64) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL10055012 | 0.85 | HDAC6 (0.67) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL30996044 | 0.85 | KMT2A (0.64) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL30996047 | 0.85 | HDAC6 (0.67) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL30996036 | 0.85 | HDAC6 (0.64) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL30996045 | 0.84 | MAPT (0.62) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL24522458 | 0.82 | HDAC6 (0.69) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL30996046 | 0.81 | HDAC6 (0.63) | KMT2AMEN1HDAC6MAPTHDAC3 | |
| SCHEMBL18434346 | 0.81 | HDAC6 (0.60) | KMT2AMEN1HDAC6MAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |