Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.84 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631403 | 0.91 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL19631345 | 0.87 | HDAC6 (0.77) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL19617676 | 0.77 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL19616918 | 0.76 | HDAC6 (0.72) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL19631312 | 0.74 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL29761213 | 0.74 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL21369247 | 0.74 | HDAC6 (0.63) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL13675666 | 0.73 | MEN1 (0.67) | HDAC6HDAC1ALDH1A1MEN1KMT2A | |
| SCHEMBL21356300 | 0.72 | HDAC6 (0.73) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL19631333 | 0.72 | HDAC6 (0.73) | HDAC6HDAC1HDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |