Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | WEE1 | P30291 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24522699 | 1.00 | KCNA3 (0.65) | KCNA3SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL24522892 | 0.88 | KCNA3 (0.70) | KCNA3SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL24523067 | 0.85 | KCNA3 (0.69) | KCNA3SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL24522709 | 0.83 | KCNA3 (0.66) | KCNA3SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL24522815 | 0.83 | KCNA3 (0.66) | KCNA3SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL24522643 | 0.83 | KDM4E (0.48) | SMN1; SMN2LMNAHPGDTP53ALDH1A1 | |
| SCHEMBL24522887 | 0.82 | KCNA3 (0.42) | KCNA3SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL24523010 | 0.82 | KCNA3 (0.76) | KCNA3SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL13609766 | 0.81 | KCNA3 (0.52) | KCNA3SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL25493370 | 0.80 | KCNA3 (0.78) | KCNA3SMN1; SMN2LMNAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022128832-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| EP-4015512-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2022-06-22 | — | — | EP | disclosed |